In 1840, Ozone was first discovered and named by German scientist C.F. Schonbein.

In 1857, the first ozone generators were developed by Werner von Siemens in Germany.

In 1870, the first report of medical grade ozone being used to purify blood in test tubes was by the German Dr. C. Lender.

In 1880, the first American therapeutic use of medical grade ozone was by Dr. John H. Kellogg in ozone steam saunas at his Battle Creek, Michigan sanitarium.

In 1893, the world's first water treatment plant using ozone was installed in Ousbaden, Holland, and today there are over 3000 municipalities around the world that use ozone to clean their water and sewage, including all the great cities.

In 1885, the Florida Medical Association published "Ozone" by Dr. Charles J. Kenworthy, MD, detailing the use of medical grade ozone for therapeutic purposes.

In 1896, the electrical genius Nikola Tesla patented his first ozone generator.

In 1898, the Institute for Oxygen Therapy Healing was started in Berlin by Thauerkauf and Luth. They experimented with injecting medical grade ozone. Medical grade Ozone was bonded to magnesium in a catalytic process to produce Homozon by Dr. Eugene Blass in 1898.

In 1898, Dr. Benedict Lust, a German doctor practicing in New York, established the practice of Naturopathy, based on medical grade ozone therapy.

In 1902, J.H. Clarke's "A Dictionary of Practical Materia Medica", London, describes the successful use of ozonated water ("Oxygenium") in treating anemia, cancer, diabetes, influenza, morphine poisoning, canker sores, strychnine poisoning and whooping cough.

In 1902, Dr. Charles Linder, MD, of Spokane, Washington was written up in an article in a local paper that stated that he injected medical grade ozone as part of his standard medical practice.

In 1904, "The Medical Uses of Hydrozone (ozonated water) and Glycozone (ozonated olive oil)" by Charles Marchand, a New York chemist appeared in its 19th edition.

In 1911, "A Working Manual of High Frequency Currents" was published by Dr. Noble Eberhart, MD, the head of the Dept. of Physiologic Therapeutics at Loyola University, Chicago. He details the use of ozone to treat tuberculosis, anemia, chlorosis, tinnitus, whooping cough, asthma, bronchitis, hay fever, insomnia, pneumonia, diabetes, gout and syphilis in his book.

In 1912, Dr. H.C. Bennett published "Electro-Therapeutic Guide". He described the use of ozone breathed after running through eucalyptus, pine or thyme oils.

In 1913, the Eastern Association for Oxygen Therapy was formed by Dr. Eugene Blass and some German associates. During World War I, (1914-1918 ) medical grade ozone was used to treat wounds, trench foot, gangrene and the effects of poison gas.

In 1915, Dr. Albert Wolff of Berlin also used medical grade ozone for colon cancer, cervical cancer and decubitus ulcers.

In 1920, Dr. Charles Neiswanger, MD, President of the Chicago Hospital College of Medicine published "Electro Therapeutical Practice". Chapter 32 was entitle "Ozone as a Therapeutic Agent".

In 1920s, Nikola Tesla allowed licensed production of an medical grade ozone air purifier in Canada, based on his cold plasma design.

In 1926, Dr. Otto Warburg of the Kaiser Institute in Berlin announced that he had found that the cause of cancer is a lack of oxygen at the cellular level. For his discovery, he was awarded the Nobel Prize for Medicine in 1931 and again in 1944, the only person ever to receive two Nobel Prizes for medicine. He was also nominated for a third.

In 1929, a book called "Ozone and Its Therapeutic Action" was published in the US listing 114 diseases and how to treat them with medical grade ozone.

In 1930, the Swiss dentist Dr. E. A. Fisch was using medical grade ozone in dentistry, and wrote many papers on it.

In 1932, Dr. E. A. Fisch was introduced medical grade Ozone Therapy to the Austrian surgeon Dr. Erwin Payr.

In 1935, M. Sourdeau published a paper on "Ozone in Therapy" in France. Dr. Aubourg and Dr. Lacoste were French physicians using medical grade ozone insufflation 1934-1938.

In 1938, Aubourg wrote "Medical Ozone: Production, Dosage and Methods of Clinical Application". He gave ozone rectally, vaginally, injected into wounds and by breathing. In 8000 applications, there were no harmful side effects.

In 1940s, Dr. Hans Wolff wrote the book "Medical Ozone". In 1942, "Gordon Detoxification and Hydro Surgery: Theory and Practice" was published covering the medical uses of ozone as colon cleanser. During World War II, Dr. Robert Mayer learned of ozone therapy from German prisoners of war at Ellis Island, and used medical grade ozone in his practice for the next 45 years.

In 1944, Dr. Otto Warburg earned his second Nobel Prize in Medicine for his discovery of the basic cause of cancer in damaged cell respiration.

In 1948, Dr. William Turska of Oregon began using a medical grade ozone machine of his own design (Aethozone).

In 1951, Dr. Turska wrote the article "Oxidation", still appropriate today.

In 1952, the National Cancer Institute verified Dr. Otto Warburg's findings regarding lack of oxygen being the cause of cancer.

From 1953, German Dr. Hans Wolff began training many doctors in medical grade ozone therapy.

In 1954, Frank Totney published "Oxygen : Master of Cancer".

In 1956, Dr. Otto Warburg published “On the Origin of Cancer Cells” in Science, 24 February 1956, Vol. 123, Num. 3191.

In 1957, Dr. J. Hansler patented an ozone generator which has formed the basis of the expansion in German ozone therapy over the last 40 years. Today, over 8000 German doctors use medical grade ozone therapy daily.

In 1961, the Encyclopedia of Chemical Technology stated: "During the 80 year history of the large scale usage of medical grade ozone, there has never been a human death attributed to it".

In 1961, Dr. Hans Wolff introduced the techniques of major and minor autohemotherapy.

In 1966, Dr. Otto Warburg, delivered a lecture on "The Prime Cause and Prevention of Cancer"  to a meeting of Nobel laureates at Lake Constance, Germany.

In 1971, Dr. Hans Wolff and Prof. Dr. Siegfried Rilling founded The German Medical Society for Medical Grade Ozone Therapy.

In 1977, Dr. Renate Viebahn provided an overview of ozone's biological action.

In 1979, Dr. George Freibott successfully treated a Haitian AIDS patient suffering Kaposi's sarcoma with medical grade ozone.

In 1980, Dr. Horst Kief also reported success with medical grade ozone therapy for AIDS patients.

In 1980, F. Sweet, et al, publish "Ozone Selectively Inhibits Human Cancer Cell Growth" in the peer-reviewed journal, Science, Vol. 209.

In 1982, the German medical textbook "Medical Ozone" is published by Dr. E. Fischer Medical Publications in Heidelberg.

In 1983, the first International Ozone Association medical ozone conference was held, in Washington, D.C., USA. The abstracts were published in the book "Medical Applications of Ozone", compiled and edited by Julius Laraus.

In 1985, Dr. Renate Viebahn published "The Biochemical Process Underlying Ozone Therapy". Dr. Siegfried Rilling published "Basic Clinical Applications of Ozone Therapy".

n 1987, Dr. Siegfried Rilling and Dr. Renate Viebahn collaborated on the publication of "The Use of Ozone in Medicine", now the standard medical text on ozone application.

Dr. Renate Viebahn Hansler ( left ; Dr. Hansler’s daughter) & Nancy ( on the right) at Egypt Ozone Conference 2006

 

In 1990, the Cubans reported success in treating glaucoma, conjunctivitis and retinitis pigmentosa with medical grade ozone.

In 1992, the Russians reported the successful use of medical grade ozone in a brine bath to treat burns.